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PolyGraft Material Technology is a Template for Healing...

hydropholic seque diagram


The hydrophilic properties and interconnected porosity of the PolyGraft material enables absorption of blood, bone marrow cells and proteins in as little as 2.5 minutes.

Staged Resorbtion... OsteoCure Biologic Scaffolds at Work

plug scheme 1

1 The scaffold is press fit into the defect site. Note the close apposition with the adjacent tissue to encourage migration of tissue into the scaffold. Using a tamp, the scaffold can be formed to match the surface geometry.







plug scheme 2


2 Immediately post implantation, the hydrophilic properties of the scaffold allow blood, marrow and progenitor cells to be wicked into the pores. The scaffold provides a porous and mechanically protected environment for healing, tissue in-growth and cellular development.





plug scheme 3


3 Between six weeks and six months, the calcium sulfate has dissolved. Progenitor cells have infiltrated the scaffold and have differentiated. New tissue has formed within the pores. The scaffold has maintained the defect walls to protect the integrity of the "zone of influence."





plug scheme 4


4 Between six months and twelve months, the polymer undergoes resorbtion and is gradually replaced with tissue. Loading is progressively transferred to condition the new tissue.







plug scheme 5


5 After twelve months, the polymer is predominantly resorbed and the defect now contains new tissue.









Supporting Documentation


Indications

The OsteoCure Plug implants are to be used to fill bony voids or gaps of the skeletal sysytem (i.e. the extremeties) caused by trauma or surgery that are not intrinsic to the stability of the bony structure.

PolyGraft® is a trademark of OsteoBiologics, Inc.

































































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